LeukoScan® (sulesomab) is a murine monoclonal IgG antibody Fab’ fragment labeled with the isotope technetium-99m. The fragment targets NCA-90, found on the cell membrane of granulocytes (a type of white blood cell). Using a gamma camera, LeukoScan® can be used to detect osteomyelitis (a bone infection). LeukoScan® is not available in North America, but it has European-wide registration and it is also approved in Australia.
Tc99m-labeled murine antibody fragment for nuclear imaging of activated granulocytes. It is approved in the European Union for diagnostic imaging for determining the location and extent of infection/inflammation in bone in patients with suspected osteomyelitis, including patients with diabetic foot ulcers.